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amie Sommers is a young woman and college dropout working at a San Francisco nightclub to support her rebellious 15-year-old sister Becca since the death of their parents. But her life changes in one night when the car Jamie is riding in with her fiancée is hit by a truck. But help arrives in the form of a top-secret government team, led by the shady Jonas Bledsoe, who saves Jamie's life by having her severely damaged legs, right arm, and right eye and ear replaced with million-dollar bionics which give Jamie superhuman abilities. But Jamie, refuses to accept this new change in her life for her responsibly to her kid sister comes first. But Jamie, the so-called 'Bionic Woman' is pressed into action when she is targeted by a certain Sarah Corvus, another bionic woman, seeking revenge against Jonas organization for construction her and betraying her to focus on Jamie.

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