ith the King of France in Naples and a peace of sorts arrived at, Rodrigo swears revenge against those who plotted against him. Cardinal Della Rovere is poisoned, though he survives the attempt on his life. Cesare and Juan continue to fight despite Rodrigo's pleas to unite with him against their enemies. Rodrigo also decides to hold a celebration for the people of Rome on a pagan feast day featuring a horse race and a large effigy of a bull. He also discovers a beautiful young woman, Vittoria, who is posing as a boy so that she can be an artists apprentice. The Pope's mistress, Giulia Farnese, is not pleased. In Naples, plague has wiped out much of the population and Prince Alfonso, who introduced the plague, is tracked down and taken prisoner.

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